FNBP1

Formin-binding protein 1 is a protein that in humans is encoded by the FNBP1 gene.

Function

The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human.

Interactions

FNBP1 has been shown to interact with:

• AKAP9,
• DNM1,
• Fas ligand
• SNX2, and
• TNKS.

References

Further reading

1. Fas ligand
2. List of human protein-coding genes 2
3. Tankyrase
4. AKAP9
5. SNX2
6. DNM1