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CENPO


CENPO


Centromere protein O is a protein that in humans is encoded by the CENPO gene. CENPO is involved in cell proliferation and cell cycle progression and has been shown to be down-regulated in trisomic neurospheres a mouse model of Down Syndrome, resulting in reduced numbers of neural progenitors and neuroblasts and a severe reduction in numbers of neurons produced.


References

External links

  • Human CENPO genome location and CENPO gene details page in the UCSC Genome Browser.

Further reading



Text submitted to CC-BY-SA license. Source: CENPO by Wikipedia (Historical)