Levocabastine

Levocabastine (trade name Livostin or Livocab, depending on the region) is a selective second-generation H₁ receptor antagonist which was discovered at Janssen Pharmaceutica in 1979. It is used for allergic conjunctivitis.

As well as acting as an antihistamine, levocabastine has also subsequently been found to act as a potent and selective antagonist for the neurotensin receptor NTS₂, and was the first drug used to characterise the different neurotensin subtypes. This has made it a useful tool for the study of this receptor.

The pharmaceutical drug Bilina is a combination of Levocabastine, benzalkonium chloride, and other components and is typically used in a 0.5 mg/ml suspension as eye-drops, dispensed in 4ml bottles for the treatment of allergic conjunctivitis or similar allergic ocular conditions.

References

External links

• "Levocabastine". Drug Information Portal. U.S. National Library of Medicine.
• "Levocabastine hydrochloride". Drug Information Portal. U.S. National Library of Medicine.

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